Substance Use Disorders

Substance use disorders are complex conditions characterized by uncontrolled use of a substance despite harmful consequences. These disorders can involve a wide range of substances, from alcohol and opioids to cannabis and stimulants.
Note: This information is provided for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
What is Substance Use Disorders?
Substance use disorders (SUDs), commonly called addictions, are chronic medical conditions characterized by problematic patterns of substance use that lead to significant impairment or distress. SUDs can involve the use of various substances, including alcohol, opioids, stimulants, cannabis, tobacco, and others. These disorders range from mild to severe, with addiction representing the most serious form. Addiction is not a moral failing or a lack of willpower—it's a complex brain disorder characterized by compulsive substance use despite negative consequences. SUDs affect brain circuits involved in reward, stress, and self-control, which can lead to intense cravings and difficulty abstaining from substance use.
Common Symptoms
The signs and symptoms of substance use disorders vary depending on the substance, but generally include the following:
- Using larger amounts of the substance or using it over a longer period than intended
- Persistent desire or unsuccessful efforts to cut down or control substance use
- Spending a great deal of time obtaining, using, or recovering from the substance
- Craving or strong urge to use the substance
- Failing to fulfill major obligations at work, school, or home due to substance use
- Continuing to use despite persistent social or interpersonal problems caused by substance use
- Giving up important occupational, social, or recreational activities because of substance use
- Using the substance in physically hazardous situations
- Continuing to use despite knowledge of a physical or psychological problem likely caused by the substance
- Tolerance (needing more of the substance to achieve the desired effect)
- Withdrawal symptoms when not using the substance
- Physical signs may include changes in appetite, weight loss or gain, deterioration of physical appearance, unusual smells on breath or clothes, impaired coordination, slurred speech, bloodshot eyes, enlarged or small pupils
- Behavioral signs may include financial problems, secretive or suspicious behavior, sudden changes in friends or activities, unexplained absences, legal issues related to substance use
Causes and Risk Factors
Substance use disorders develop due to a combination of genetic, environmental, and developmental factors. Risk factors include genetic predisposition (family history of SUDs), early exposure to substances, trauma or adverse childhood experiences, mental health disorders, peer pressure, lack of family involvement, and high levels of stress. The initial decision to use substances is typically voluntary, but repeated use can lead to brain changes that challenge an addicted person's self-control and ability to resist intense urges to use substances.
Common Treatment Approaches
Substance use disorders are treatable, and recovery is possible. Treatment approaches vary depending on the specific substance and the individual's needs but often include a combination of the following:
Therapy Options
Behavioral therapies are the most commonly used treatments for SUDs. Cognitive Behavioral Therapy (CBT) helps identify and change negative thought patterns and behaviors related to substance use. Motivational Enhancement Therapy (MET) helps individuals resolve ambivalence about treatment and stopping substance use. Contingency Management provides incentives for positive behaviors like abstinence. Other effective approaches include family therapy, group therapy, and 12-step facilitation therapy, which prepares individuals to engage in 12-step programs like Alcoholics Anonymous (AA) or Narcotics Anonymous (NA).
Medication Options
Medications are available to treat certain substance use disorders, particularly opioid, alcohol, and tobacco use disorders. For opioid use disorder, medications include methadone, buprenorphine, and naltrexone. For alcohol use disorder, medications include acamprosate, disulfiram, and naltrexone. For tobacco use disorder, nicotine replacement therapy, bupropion, and varenicline can be effective. These medications can help manage withdrawal symptoms, reduce cravings, and prevent relapse.
Self-Care Strategies
Self-care strategies can support recovery from substance use disorders:
- Engage in regular physical activity and maintain a healthy diet
- Develop healthy sleep habits
- Practice stress management techniques like meditation, deep breathing, or yoga
- Build a strong support network of friends, family, and peers in recovery
- Attend support group meetings regularly
- Identify and avoid triggers for substance use
- Develop healthy coping mechanisms for stress, cravings, and negative emotions
- Set realistic goals and celebrate achievements in recovery
- Find meaningful activities that don't involve substance use
- Seek help promptly if experiencing a relapse or increased cravings
When to Seek Professional Help
If you or someone you know is struggling with substance use, it's important to seek help. Signs that substance use has become problematic include using more than intended, being unable to cut down, experiencing withdrawal symptoms, neglecting responsibilities, and continuing to use despite negative consequences. Treatment options include talking to a healthcare provider, contacting SAMHSA's National Helpline (1-800-662-HELP), attending a 12-step or other support group meeting, or visiting an addiction treatment center. If someone is experiencing a medical emergency related to substance use, call 911 immediately.
Quick Facts
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Approximately 20.4 million people in the U.S. aged 12 or older had a substance use disorder in 2019.
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Of those, 14.5 million had an alcohol use disorder, 8.3 million had an illicit drug use disorder, and 2.4 million had both.
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Only about 10% of people with a substance use disorder receive treatment.
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Relapse rates for substance use disorders are similar to those for other chronic medical conditions like diabetes and hypertension (40-60%).
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Recovery is possible, and many people recover from substance use disorders and lead healthy, productive lives.
Related Conditions
Resources
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